Living with hATTR
hATTR is difficult to live with(1,2)

Living with hATTR

hATTR is difficult to live with(1,2)

hATTR is difficult to live with1,2


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About hATTR

About hATTR

Hereditary transthyretin amyloidosis is a rapidly progressive and life-shortening disease

Disease mechanism

Disease mechanism

Mechanism of TTR amyloid formation

Symptoms

Symptoms

Red flag symptoms

Diagnosis

Diagnosis

Clinical suspicion index varies between endemic and non-endemic areas3

Disease progression

Disease progression

hATTR is progressive and physical function deteriorates rapidly4

About Tegsedi

About Tegsedi

For your hATTR patients with stage 1 or 2 polyneuropathy, what matters is now

References
  1. Gertz MA. Hereditary ATTR amyloidosis: burden of illness and diagnostic challenges. Am J Manag Care. 2017;23(suppl 7):S107–S112.
  2. Amyloidosis Foundation. Understanding the patient voice in hereditary transthyretin-mediated amyloidosis (ATTR amyloidosis). Available at: https://www.amyloidosissupport.org/support_groups/fam_isabell_attr.pdf. Accessed April 2020.
  3. Adams D, Ando Y et al., J Neurol. 2021 Jun;268(6):2109-212.
  4. Monteiro C, Mesgazardeh JS et al. Predictive model of response to tafamidis in hereditary ATTR polyneuropathy. JCI Insight. 2019 Jun 20;4(12):e126526